Which enterovirus is most commonly associated with herpangina?

Herpangina is an illness that primarily affects children and is characterized by the acute onset of fever, sore throat, and the development of small, painful ulcers in the mouth and throat. The condition is most commonly caused by Coxsackievirus, a member of the Enterovirus family. This virus is known for its affinity for the mucous membranes of the oropharynx, leading to the symptomatic presentation associated with herpangina.

Coxsackievirus, particularly the A16 strain, has been specifically linked to outbreaks of herpangina among young children. Its transmission is typically through fecal-oral routes or respiratory droplets, facilitating the spread in child care settings. The pathophysiology of herpangina involves the virus infecting the epithelial cells of the oropharynx, causing localized inflammation and the formation of vesicular lesions.

The other viruses mentioned do not have the same association with herpangina. For instance, Parvovirus B19 is primarily known for causing fifth disease and affects red blood cell production. Adenovirus can cause a variety of illnesses, including respiratory infections and conjunctivitis, but it is not typically associated with herpangina. Epstein-Barr virus is primarily connected with infectious mononucleosis and