Which HPV subtypes are primarily associated with cervical cancer?

Human Papillomavirus (HPV) is a group of more than 200 related viruses, some of which are known to be high-risk types associated with cervical cancer. Among these, HPV subtypes 16 and 18 are particularly significant, as they are identified globally as the primary oncogenic (cancer-causing) types. These two subtypes account for approximately 70% of all cervical cancer cases.

HPV 16 is the most prevalent subtype in cervical cancer cases, while HPV 18 is also commonly found but to a slightly lesser extent. Both of these types lead to the development of cervical intraepithelial neoplasia (CIN), which, if untreated, can progress to cervical cancer over time. The recognition of these particular subtypes emphasizes the importance of vaccination and screening strategies aimed at preventing cervical cancer.

In contrast, the other options listed do not include the primary subtypes linked with cervical cancer. While there are other HPV types that may contribute to cancer risk, they do not have the same strong association or prevalence as HPV 16 and 18 in the context of cervical cancer. Therefore, the identification of HPV 16 and 18 as the primary subtypes underscores the critical role of these specific viruses